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| Catalog Number | Size | Price |
|---|---|---|
| LS-C45257-0.25 | 0.25 mg (0.5 mg/ml) | $486 |
Monoclonal Mouse anti‑Rat ITGAM / CD11b Antibody (clone ED7, IHC) LS‑C45257
Monoclonal Mouse anti‑Rat ITGAM / CD11b Antibody (clone ED7, IHC) LS‑C45257
Antibody:
ITGAM / CD11b Mouse anti-Rat Monoclonal (ED7) Antibody
Application:
IHC, IHC-Fr, Flo
Reactivity:
Rat
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ITGAM / CD11b Mouse anti-Rat Monoclonal (ED7) Antibody
Application:
IHC, IHC-Fr, Flo
Reactivity:
Rat
Format:
Unconjugated, Unmodified
Specifications
Description
CD11b antibody LS-C45257 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for Flow and IHC.
Target
Rat ITGAM / CD11b
Synonyms
ITGAM | Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain
Host
Mouse
Reactivity
Rat
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
ED7
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Rat spleen cell homogenate.
Specificity
Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Like ED8, Recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED7, except for the cilia of the bronchus epithelium. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules (CD11b/CD18). ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.
Applications
- IHC
- IHC - Frozen (1:500)
- Flow Cytometry
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ITGAM / CD11b
Publications (0)
Customer Reviews (0)
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Species:
Mouse, Human, Rabbit
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Immunofluorescence, Immunoprecipitation, Flow Cytometry
Species:
Mouse, Human, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Dog, Bovine, Cat, Goat, Pig, Mustelid
Applications:
IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
