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FGF8

fibroblast growth factor 8 (androgen-induced)

FGF8 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.

Gene Name: fibroblast growth factor 8 (androgen-induced)
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF8, AIGF, Androgen-induced growth factor, FGF-8, Fibroblast growth factor 8, HBGF-8, KAL6, HH6
Target Sequences: NM_006119 NP_006110.1

Publications (1)

1
Dynamic secretion during meiotic reentry integrates the function of the oocyte and cumulus cells. Hakan Cakmak, Federica Franciosi, A Musa Zamah, Marcelle I Cedars, Marco Conti. Proceedings of the National Academy of Sciences of the United States of America. 2016 March;113:2424-9. [Full Text Article] [PubMed:26864200] [PMC:PMC4780620]

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FGF8 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FGF8 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
FGF8 Antibody - FGF8 antibody Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FGF8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
FGF8 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
FGF8 Antibody - FGF8 monoclonal antibody (M01), clone 2A10. Western Blot analysis of FGF8 expression in PC-12.
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FGF8 Mouse anti-Human Monoclonal (2A10) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$423
FGF8 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Select
FGF8 Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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FGF8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
FGF8 Antibody - Western blot analysis of FGF8 expression in Jurkat cell lysates in RIPA buffer. The lane on the left is treated with the antigen-specific peptide.
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FGF8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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FGF8 Rabbit anti-Mouse Polyclonal (aa30-59) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
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FGF8 Rabbit anti-Mouse Polyclonal (aa30-59) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
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FGF8 Rabbit anti-Mouse Polyclonal (aa30-59) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
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FGF8 Rabbit anti-Mouse Polyclonal (aa30-59) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
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FGF8 Rabbit anti-Mouse Polyclonal (aa30-59) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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FGF8 Rabbit anti-Mouse Polyclonal (aa30-59) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
FGF8 Antibody - Immunohistochemistry of paraffin-embedded human ovarian cancer using FGF8 Antibody at dilution of 1:100
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FGF8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
Select
FGF8 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
FGF8 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
FGF8 Antibody - Western blot - Anti-FGF8 Picoband Antibody
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FGF8 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
FGF8 Antibody - Western Blot analysis of extracts from K562 cells using FGF8 Antibody.
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FGF8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
FGF8 Antibody - IHC-P: FGF8 antibody testing of rat ovary tissue
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FGF8 Rabbit anti-Human Polyclonal (aa192-214) Antibody
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Human
IHC-P, WB
Unconjugated
100 µg/$575
FGF8 Antibody - Mouse Fgf8 Antibody western blot of mouse NIH-3T3 cell line lysates (35 ug/lane). The Mouse Fgf8 antibody detected the Mouse Fgf8 protein (arrow).
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FGF8 Rabbit anti-Mouse Polyclonal (aa30-59) Antibody
Mouse
WB
Unconjugated
400 µl/$393
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FGF8 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$412
FGF8 Antibody - FGF8 antibody Western Blot of PANC1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FGF8 Rabbit anti-Human Polyclonal (aa104-153) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
FGF8 Antibody - Western blot of lysates from HepG2, HeLa, Jurkat, MCF-7, LNCaP, HT-1080 cell line (from left to right) with FGF8 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
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FGF8 Rabbit anti-Human Polyclonal (aa32-66) Antibody
Human
WB
Unconjugated
400 µl/$393
Viewing 1-25 of 48 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).