Zyxin

Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

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Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

Zyxin (8)

Publications

No (8)

Tag

6His, N-terminus (1)

GST (1)

His (2)

Myc-DDK (Flag) (4)

Species

Human (7)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (3)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human Zyxin Protein (Recombinant 6His, N-terminus) (aa2-572) - LS-G57066

Source:

Mammalian Cells

Tag:

6His, N-terminus

Price:

100 µg/$1,009; 20 µg/$431; 1 mg/$3,451

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Human Zyxin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67368

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.1 kDa

Price:

20 µg/$1,107

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Human Zyxin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67370

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.1 kDa

Price:

20 µg/$1,107

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Human Zyxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79688

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.1 kDa

Price:

20 µg/$215

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Human Zyxin Protein (Recombinant His) (aa377-523) - LS-G14846

Source:

E. coli

Tag:

His

Molecular Weight:

17.9 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human Zyxin Protein (Recombinant His) (aa384-572) - LS-G14845

Source:

E. coli

Tag:

His

Molecular Weight:

22.6 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human Zyxin Protein (Recombinant GST) (Full Length) - LS-G31003

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88.66 kDa

Price:

10 µg/$479; 25 µg/$670

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Zyxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117319

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.1 kDa

Price:

100 µg/$710

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