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ZRANB3

Zinc Finger, RAN-binding Domain Containing 3

DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks.

Gene Name: Zinc Finger, RAN-binding Domain Containing 3
Synonyms: ZRANB3, Annealing helicase 2, DKFZP434B1727, AH2
Target Sequences: NM_032143 NP_115519.2 Q5FWF4

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Products
Antibodies (12)
Primary (12)
ZRANB3 (12)
Human (12)
Mouse (2)
Rat (2)
IHC (1)
WB (8)
ELISA (5)
IF (1)
IP (1)
rabbit (12)
IgG (8)
polyclonal pc (12)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (6)
aa640-689 (4)
aa1029-1079 (1)
No (12)
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ZRANB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ZRANB3 Antibody - Immunohistochemistry of paraffin-embedded human adrenal gland tissue using ZRANB3 Antibody at dilution of 1:100
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ZRANB3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
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ZRANB3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ZRANB3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ZRANB3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
ZRANB3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
Select
ZRANB3 Rabbit anti-Human Polyclonal (aa1029-1079) Antibody
Human
IP, WB
Unconjugated
100 µl/$467
Select
ZRANB3 Rabbit anti-Human Polyclonal (aa640-689) Antibody
Human
WB
Unconjugated
100 µl/$424
Select
ZRANB3 Rabbit anti-Human Polyclonal (aa640-689) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
Select
ZRANB3 Rabbit anti-Human Polyclonal (aa640-689) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
Select
ZRANB3 Rabbit anti-Human Polyclonal (aa640-689) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
Select
ZRANB3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).