ZP3

zona pellucida glycoprotein 3 (sperm receptor)

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene.

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Products

Antibodies (18)

ELISA Kits (8)

Proteins (8)

Type

Custom (6)

Over-Expression Lysate (4)

Primary (18)

Recombinant (4)

Sandwich (2)

Target

ZP3 (34)

Reactivity

Human (20)

Mouse (2)

Rat (3)

Bovine (3)

Chicken (1)

Dog (1)

Horse (3)

Pig (1)

Rabbit (3)

Application

IHC (1)

WB (16)

ELISA (7)

IF (2)

Host

rabbit (18)

Isotype

IgG (17)

Clonality

polyclonal pc (18)

Format

96-Well Strip Plate (8)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (10)

Epitope

aa353-380 (7)

C-Terminus (4)

Publications

No (34)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

GST (2)

Myc-DDK (Flag) (4)

Species

Human (6)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

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ZP3 Antibody (C-Terminus) LS-C31621

Antibody:

ZP3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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ZP3 Antibody (C-Terminus, HRP) LS-C433270

Antibody:

ZP3 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Bovine, Horse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

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ZP3 Antibody (C-Terminus, Biotin) LS-C433268

Antibody:

ZP3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Bovine, Horse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

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ZP3 Antibody (C-Terminus, FITC) LS-C433269

Antibody:

ZP3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Bovine, Horse, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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ZP3 Antibody LS-C660825

Antibody:

ZP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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Human ZP3 Protein (Recombinant GST) (aa23-346) - LS-G22639

Source:

E. coli

Tag:

GST

Molecular Weight:

63.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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ZP3 Antibody LS-C833056

Antibody:

ZP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ZP3 Antibody (aa353-380) LS-C326739

Antibody:

ZP3 Rabbit anti-Human Polyclonal (aa353-380) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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ZP3 Antibody (aa353-380, Biotin) LS-C274690

Antibody:

ZP3 Rabbit anti-Human Polyclonal (aa353-380) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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ZP3 Antibody (aa353-380, FITC) LS-C274691

Antibody:

ZP3 Rabbit anti-Human Polyclonal (aa353-380) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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ZP3 Antibody (aa353-380, APC) LS-C274689

Antibody:

ZP3 Rabbit anti-Human Polyclonal (aa353-380) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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ZP3 Antibody (aa353-380, Azide-free, HRP) LS-C274692

Antibody:

ZP3 Rabbit anti-Human Polyclonal (aa353-380) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

ZP3 Antibody (aa353-380, PE) LS-C274693

Antibody:

ZP3 Rabbit anti-Human Polyclonal (aa353-380) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

ZP3 Antibody LS-C834533

Antibody:

ZP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ZP3 Antibody (aa353-380) LS-C157522

Antibody:

ZP3 Rabbit anti-Human Polyclonal (aa353-380) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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ZP3 Antibody LS-C748214

Antibody:

ZP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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ZP3 Antibody LS-C409891

Antibody:

ZP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

ZP3 Antibody LS-C782868

Antibody:

ZP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

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ZP3 Antibody LS-C796582

Antibody:

ZP3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$414

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Human ZP3 Protein (Recombinant 6His-SUMO, N-terminus) (aa23-387) - LS-G56627

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human ZP3 Protein (Recombinant 6His, N-terminus) (aa23-387) - LS-G57069

Source:

Mammalian Cells

Tag:

6His, N-terminus

Price:

100 µg/$1,009; 20 µg/$431; 1 mg/$3,451

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Human ZP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79684

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.1 kDa

Price:

20 µg/$150

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Human ZP3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79683

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.1 kDa

Price:

20 µg/$150

Select

Mouse ZP3 (Custom ELISA) ELISA Kit - LS-F16373

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Pig ZP3 (Custom ELISA) ELISA Kit - LS-F16374

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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