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ZNF384

zinc finger protein 384

ZNF384 is a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.

Gene Name: zinc finger protein 384
Synonyms: ZNF384, CIZ, CAG repeat protein 1, CAGH1, ERDA2, NP, Nuclear matrix protein 4, Zinc finger protein 384, CAGH1A, NMP4, TNRC1
Target Sequences: U80760 AAB91437.1 Q8TF68

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Proteins (10)
Over-Expression Lysate (8)
Recombinant (2)
ZNF384 (10)
No (10)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (8)
Human (6)
293T Cells (4)
E. coli (2)
HEK 293 Cells (4)
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.9 kDa
100 µg/$710
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.9 kDa
100 µg/$710
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.9 kDa
100 µg/$710
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
50.4 kDa
100 µg/$494
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E. coli
GST
53.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ZNF384 Protein - Recombinant  Nuclear Matrix Protein 4 By SDS-PAGE
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E. coli
His-T7
29.8 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.9 kDa
20 µg/$215
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.9 kDa
20 µg/$215
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.9 kDa
20 µg/$215
ZNF384 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
50.4 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).