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ZKSCAN3 / ZNF306
zinc finger with KRAB and SCAN domains 3
Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.
| Gene Name: | zinc finger with KRAB and SCAN domains 3 |
| Family/Subfamily: | Zinc Finger |
| Synonyms: | ZKSCAN3, DJ874C20.1, DJ874C20.1., KIAA0426, Zfp-47, ZFP306, Zinc finger protein 309, ZNF306, ZNF309, ZSCAN13, ZSCAN35, ZF47, Zinc finger protein 306, Zinc finger protein zfp47, Zfp47, Zinc finger protein 47 homolog |
| Target Sequences: | U71601 AAB16813.1 |
Publications (1)
1
Alcohol-Induced Lysosomal Damage and Suppression of Lysosome Biogenesis Contribute to Hepatotoxicity in HIV-Exposed Liver Cells. Moses New-Aaron , Paul G Thomes , Murali Ganesan , Raghubendra Singh Dagur , Terrence M Donohue Jr , Kharbanda K Kusum , Larisa Y Poluektova, Natalia A Osna. Biomolecules. 2021 Oct;11:1497. [Full Text Article]
[PubMed:34680130]
[PMC:PMC8533635]
Related Antibodies: LS-C501696.
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(6)
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Primary
(15)
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ZKSCAN3 / ZNF306
(21)
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(15)
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(11)
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(1)
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rabbit
(14)
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(12)
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(1)
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(1)
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(14)
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(2)
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(2)
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(2)
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(9)
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(4)
aa1-394
(1)
aa100-130
(1)
aa175-440
(1)
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(20)
Yes
(1)
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GST
(2)
GST, N-terminus
(1)
Myc-DDK (Flag)
(3)
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(5)
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293T Cells
(1)
HEK 293 Cells
(2)
Wheat Germ Extract
(3)
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Purified
(2)
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (aa1-394) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ZKSCAN3 / ZNF306 Mouse anti-Human Monoclonal (2A5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (aa175-440) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$332
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal (aa100-130) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
ZKSCAN3 / ZNF306 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
60.5 kDa
20 µg/$1,107
293T Cells
Myc-DDK (Flag)
60.5 kDa
20 µg/$150
Wheat Germ Extract
GST
84.7 kDa
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST
87 kDa
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
60.5 kDa
100 µg/$494
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