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ZIF268 / EGR1

early growth response 1

EGR-1 (also called Early Growth Response protein 1, Krox-24 protein, ZIF268, Nerve growth factor-induced protein A or NGFI-A, Transcription factor ETR103, and Zinc finger protein 225 or AT225) is a transcriptional regulator that recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3' (EGR-site). EGR1 has been implicated in diverse roles in the regulation of cell growth, apoptosis, and differentiation. EGR-1 activates the transcription of target genes whose products are required for mitogenesis and differentiation. EGR-1 is a nuclear protein induced by growth factors.

Gene Name: early growth response 1
Synonyms: EGR1, AT225, Early growth response 1, G0S30, KROX24, NGFIA, KROX-24, TIS8, ZIF-268, ZIF268, Zinc finger protein Krox-24, EGR-1, NGFI-A, Transcription factor ETR103, Transcription factor Zif268, Zinc finger protein 225
Target Sequences: NM_001964 NP_001955.1 P18146

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).