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Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes.
Gene Name: | zinc finger, AN1-type domain 6 |
Family/Subfamily: | Zinc Finger |
Synonyms: | ZFAND6, AN1-type zinc finger protein 6, Associated with PRK1 protein, AWP1, Protein associated with PRK1, ZA20D3, ZFAND5B, Zinc finger, AN1-type domain 6 |
Target Sequences: | NM_019006 NP_061879.2 Q6FIF0 |
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