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ZFAND5

zinc finger, AN1-type domain 5

Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.

Gene Name: zinc finger, AN1-type domain 5
Family/Subfamily: Zinc Finger
Synonyms: ZFAND5, AN1-type zinc finger protein 5, Zinc finger protein 216, Zinc finger, AN1-type domain 5, ZNF216, ZA20D2, ZFAND5A
Target Sequences: NM_006007 NP_005998.1 O76080

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (6)
Recombinant (7)
ZFAND5 (13)
No (13)
DDK,C-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (9)
Human (10)
293T Cells (3)
E. coli (1)
HEK 293 Cells (6)
Sf9 Cells (1)
Wheat Germ Extract (2)
Purified (2)
ZFAND5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
23 kDa
20 µg/$150
ZFAND5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23 kDa
20 µg/$150
ZFAND5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23 kDa
20 µg/$150
ZFAND5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23 kDa
100 µg/$494
ZFAND5 Protein
Select
Sf9 Cells
DDK,C-terminus
23.1 kDa
20 µg/$677
ZFAND5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23 kDa
100 µg/$494
ZFAND5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23 kDa
100 µg/$494
ZFAND5 Protein - 12.5% SDS-PAGE of human ZFAND5 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.5 kDa
10 µg/$479; 25 µg/$670
ZFAND5 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
ZFAND5 Protein - Purified recombinant protein ZFAND5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23 kDa
20 µg/$1,107
ZFAND5 Protein - Purified recombinant protein ZFAND5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23 kDa
20 µg/$1,107
ZFAND5 Protein - Purified recombinant protein ZFAND5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23 kDa
20 µg/$1,107
ZFAND5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-13 of 13 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).