ZBP1

Z-DNA binding protein 1

Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3.

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Products

Proteins (10)

Type

Over-Expression Lysate (4)

Recombinant (6)

Target

ZBP1 (10)

Publications

No (10)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His, N-Terminal (2)

Myc-DDK (Flag) (4)

Species

Human (8)

Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (2)

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Human ZBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91984

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.2 kDa

Price:

20 µg/$215

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Human ZBP1 Protein (Recombinant His, N-Terminal) (Arg10-Pro167) - LS-G13976

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

19.4 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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ZBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128068

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38 kDa

Price:

100 µg/$494

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Human ZBP1 Protein (Recombinant GST) (Full Length) - LS-G35477

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

42.4 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ZBP1 Protein (Recombinant 6His, C-terminus) (Met1-Ser149) - LS-G140464

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17.5 kDa

Price:

10 µg/$317; 50 µg/$524

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Human ZBP1 Protein (Recombinant His, N-Terminal) - LS-G144166

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

46.2 kDa

Price:

50 µg/$419

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Human ZBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91982

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38 kDa

Price:

20 µg/$150

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Human ZBP1 Protein (Recombinant GST, N-terminus) (aa2-100) - LS-G63267

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ZBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101962

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.2 kDa

Price:

100 µg/$710

Select

Human ZBP1 Protein (Recombinant 6His, C-terminus) (Met1-Ser149) - LS-G38815

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17.5kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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