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YWHAG / 14-3-3 Gamma

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

YWHAG / 14-3-3 Gamma belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
Synonyms: YWHAG, 14-3-3GAMMA, 14-3-3 gamma, 14-3-3 protein gamma, KCIP-1
Target Sequences: NM_012479 NP_036611.2 P61981

Publications (2)

1
Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression. Hu X, Addlagatta A, Lu J, Matthews BW, Liu JO. Proceedings of the National Academy of Sciences of the United States of America. 2006 103:18148-53. [PubMed:17114291] [PMC:PMC1838721]
2
Effect of nitroxoline on angiogenesis and growth of human bladder cancer. Shim JS, Matsui Y, Bhat S, Nacev BA, Xu J, Bhang HE, Dhara S, Han KC, Chong CR, Pomper MG, So A, Liu JO. Journal of the National Cancer Institute. 2010 102:1855-73. (WB; Mouse, Human) [PubMed:21088277] [PMC:PMC3001967]

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Products
Proteins (8)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (4)
YWHAG / 14-3-3 Gamma (8)
No (8)
6His, N-terminus (2)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
HEK 293 Cells (4)
Wheat Germ Extract (3)
Purified (1)
YWHAG / 14-3-3 Gamma Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
YWHAG / 14-3-3 Gamma Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
YWHAG / 14-3-3 Gamma Protein - Purified recombinant protein YWHAG was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
28.1 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
28.1 kDa
20 µg/$150
YWHAG / 14-3-3 Gamma Protein - 12.5% SDS-PAGE of human YWHAG stained with Coomassie Blue
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Wheat Germ Extract
GST
52.91 kDa
2 µg/$439
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HEK 293 Cells
6His, N-terminus
28 kDa
200 µl/$283
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HEK 293 Cells
6His, N-terminus
28 kDa
100 µg/$298
YWHAG / 14-3-3 Gamma Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
28.1 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).