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XRN2
5'-3' exoribonuclease 2
Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription.
| Gene Name: | 5'-3' exoribonuclease 2 |
| Synonyms: | XRN2, 5'-3' exoribonuclease 2, 5-3 exoribonuclease 2, DHM1-like protein, DHP protein |
| Target Sequences: | NM_012255 NP_036387.2 Q9H0D6 |
Publications (1)
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