XRN1

5'-3' exoribonuclease 1

XRN1 is a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

XRN1 (5)

Publications

No (5)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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Rat XRN1 Protein (Recombinant) (Phe1567-Glu1723) - LS-G133745

Source:

E. coli

Tag:

None

Molecular Weight:

20.4kDa

Price:

10 µg/$288; 50 µg/$482; 200 µg/$965; 100 µg/$772; 1 mg/$2,098; 500 µg/$1,627; 5 mg/$3,375; 2 mg/$2,288

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Human XRN1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87680

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

193.9 kDa

Price:

20 µg/$215

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XRN1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111519

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

193.9 kDa

Price:

100 µg/$710

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Human XRN1 Protein (Recombinant GST) (Full Length) - LS-G33976

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human XRN1 Protein (Recombinant) (Tyr1394-Glu1706) - LS-G133669

Source:

E. coli

Tag:

None

Molecular Weight:

37.4kDa

Price:

10 µg/$283; 50 µg/$452; 200 µg/$905; 100 µg/$725; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

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