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Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.
Gene Name: | XK, Kell Blood Group Complex Subunit-related Family, Member 8 |
Synonyms: | XKR8, RP11-460I13.3, XK-related protein 8, XRG8 |
Target Sequences: | NM_018053 NP_060523.2 Q9H6D3 |
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