XRCC2

X-ray repair complementing defective repair in Chinese hamster cells 2

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

XRCC2 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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XRCC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115964

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.8 kDa

Price:

100 µg/$494

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Human XRCC2 Protein (Recombinant GST) (Full Length) - LS-G30916

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

56.54 kDa

Price:

10 µg/$479; 25 µg/$670

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Human XRCC2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70043

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.8 kDa

Price:

20 µg/$1,107

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Human XRCC2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86146

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.8 kDa

Price:

20 µg/$150

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