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XRCC2

X-ray repair complementing defective repair in Chinese hamster cells 2

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.

Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 2
Synonyms: XRCC2, DNA repair protein XRCC2
Target Sequences: NM_005431 NP_005422.1 O43543

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Products
Antibodies (26)
Primary (26)
XRCC2 (26)
Human (26)
Mouse (8)
Rat (6)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
Rabbit (3)
IHC (10)
IHC-P (3)
WB (22)
ELISA (10)
ICC (1)
IF (6)
Peptide-ELISA (2)
rabbit (25)
mouse (1)
IgG (16)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (25)
2H4 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (18)
aa1-30 (7)
aa144-193 (4)
180-260 aa, C-terminal (1)
C-Terminus (1)
Phe240 (1)
aa1-123 (1)
aa211-260 (1)
No (26)
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
XRCC2 Antibody - Immunohistochemistry of paraffin-embedded human thyroid cancer using XRCC2 antibodyat dilution of 1:200 (40x lens).
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
XRCC2 Antibody - Immunofluorescence of monoclonal antibody to XRCC2 on HeLa cell . [antibody concentration 10 ug/ml]
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XRCC2 Mouse anti-Human Monoclonal (2H4) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
XRCC2 Antibody - Immunofluorescence staining of XRCC2 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human XRCC2 polyclonal antibody (dilution ratio 1:1000) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
XRCC2 Antibody - Western blot of XRCC2 antibody
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XRCC2 Rabbit anti-Human Polyclonal (180-260 aa, C-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
XRCC2 Antibody - IHC of XRCC2 (F240) pAb in paraffin-embedded human lung carcinoma tissue.
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XRCC2 Rabbit anti-Human Polyclonal (Phe240) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
XRCC2 Antibody - Immunohistochemical analysis of XRCC2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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XRCC2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
XRCC2 Antibody - 1:100 staining mouse spleen tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
XRCC2 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using XRCC2 Antibody. The picture on the right is blocked with the synthesized peptide.
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XRCC2 Rabbit anti-Human Polyclonal (aa211-260) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
XRCC2 Antibody - Immunofluorescence analysis of A549 cells using XRCC2 antibody. Blue: DAPI for nuclear staining.
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
XRCC2 Antibody - Western blot of extracts of various cell lines, using XRCC2 antibody.
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
XRCC2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using XRCC2 antibody.
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$357
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XRCC2 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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XRCC2 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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XRCC2 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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XRCC2 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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XRCC2 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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XRCC2 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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XRCC2 Rabbit anti-Human Polyclonal Antibody
Human
IHC
Unconjugated
50 µg/$305; 100 µg/$357
XRCC2 Antibody - XRCC2 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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XRCC2 Rabbit anti-Human Polyclonal (aa144-193) Antibody
Human
WB
Unconjugated
100 µl/$424
XRCC2 Antibody - XRCC2 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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XRCC2 Rabbit anti-Human Polyclonal (aa144-193) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
XRCC2 Antibody - XRCC2 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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XRCC2 Rabbit anti-Human Polyclonal (aa144-193) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
XRCC2 Antibody - XRCC2 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The XRCC2 antibody detected the XRCC2 protein (arrow).
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XRCC2 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
WB
Unconjugated
400 µl/$393
XRCC2 Antibody - Sample. A:30g of Raji whole cell lysate . 12% SDS PAGE. XRCC2 antibody diluted at 1:1000
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XRCC2 Rabbit anti-Human Polyclonal (aa1-123) Antibody
Human
WB
Unconjugated
100 µl/$450
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).