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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
| Gene Name: | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| Synonyms: | XRCC1, RCC, DNA repair protein XRCC1 |
| Target Sequences: | NM_006297 NP_006288.2 P18887 |
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