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XAGE2 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewing's sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens.
Gene Name: | X antigen family, member 2 |
Synonyms: | XAGE2, Cancer/testis antigen 12.2, CT12.2, GAGED3, G antigen family D member 3, Protein XAGE-2, XAGE-2, G antigen, family D, 3, X antigen family, member 2 |
Target Sequences: | Q96GT9 Q96GT9 |
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