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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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WWOX

WW domain containing oxidoreductase

Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.

Gene Name: WW domain containing oxidoreductase
Synonyms: WWOX, D16S432E, FRA16D, FOR, HHCMA56, PRO0128, SDR41C1, WOX1
Target Sequences: NM_016373 NP_057457.1 Q9NZC7

Filtered by: None
Target
WWOX (41)
Reactivity
Human (35)
Mouse (27)
Rat (9)
Bovine (6)
Chicken (1)
Chimpanzee (3)
Guinea pig (4)
Hamster (1)
Horse (4)
Orangutan (3)
Zebrafish (1)
Application
IHC (13)
IHC-P (6)
WB (35)
ELISA (16)
ICC (2)
IF (5)
IP (2)
Peptide-ELISA (2)
Host
rabbit (40)
sheep (1)
Isotype
IgG (27)
Clonality
polyclonal pc (41)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (26)
Epitope
aa369-396 (8)
N-Terminus (6)
aa95-144 (4)
1-80 aa, N-terminal (1)
10-90 aa (1)
Ala7 (1)
aa1-50 (1)
aa36-126 (1)
aa364-414 (1)
aa75-125 (1)
aa89-107 (1)
pTyr33 (1)
Publications
No (41)
Showing 1-25 of 41 results

IHC-plus™ WWOX Antibody LS-B8928
Rabbit Polyclonal to Human WWOX
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-WWOX antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunofluorescence of paraformaldehyde-fixed A549, using WWOX antibody at 1:200 dilution.

WWOX Antibody (N-Terminus) LS-C358885
Rabbit Polyclonal to Human WWOX
Mouse, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30µl 1mg/ml  $205.00; 100µl 1mg/ml  $245.00; 200µl 1mg/ml  $305.00
Immunohistochemical analysis of WWOX staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of WWOX staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

WWOX Antibody LS-C662513
Rabbit Polyclonal to Human WWOX
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg  $325.00
Immunohistochemistry - Anti-WWOX Picoband antibody
Immunohistochemistry - Anti-WWOX Picoband antibody

WWOX Antibody LS-C671929
Rabbit Polyclonal (IgG) to Human WWOX
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human placenta tissue at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human testis tissue at a dilution of 1:100

WWOX Antibody (1-80 aa, N-terminal) LS-C386672
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

IHC-plus™ WWOX Antibody (N-Terminus) LS-B14572
Rabbit Polyclonal to Human WWOX
Chicken, Zebrafish, Mouse, Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

WWOX Antibody (Ala7) LS-C176984
Rabbit Polyclonal to Human WWOX
Mouse, Human
IF, IHC, WB
Unconjugated
100µl  $345.00
Western blot of WWOX (A7) pAb in extracts from HepG2 cells.

WWOX Antibody (phospho-Tyr33) LS-C199736
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using WWOX (Phospho-Tyr33) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of lysates from HepG2 cells treated with PMA 125ng/ml 30', using WWOX (Phospho-Tyr33) Antibody. The lane on the right is blocked with the phospho peptide.

WWOX Antibody (aa89-107) LS-C40750
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Bovine, Rat, Hamster, Human
ELISA, IHC, WB
Unconjugated
100µg 100µl 1mg/ml  $275.00

WWOX Antibody (10-90 aa) LS-C381404
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

WWOX Antibody LS-C771847
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl 0.4mg/ml  $205.00; 60µl 0.4mg/ml  $235.00; 120µl 0.4mg/ml  $295.00; 200µl 0.4mg/ml  $395.00

WWOX Antibody LS-C804712
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

WWOX Antibody (aa364-414) LS-C290724
Rabbit Polyclonal (IgG) to Human WWOX
Human
IHC, IP
Unconjugated
100µl 1mg/ml  $395.00

WWOX Antibody (aa75-125) LS-C290723
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
IHC, IP
Unconjugated
100µl 1mg/ml  $395.00

WWOX Antibody (aa369-396) LS-C326381
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
ELISA, WB
Unconjugated
200µl  $590.00

WWOX Antibody (aa369-396, Biotin) LS-C224669
Rabbit Polyclonal (IgG) to Mouse WWOX
Mouse
ELISA, WB
Biotin Conjugated
200µl  $740.00

WWOX Antibody (aa369-396, FITC) LS-C224670
Rabbit Polyclonal (IgG) to Mouse WWOX
Mouse
ELISA, WB
FITC Conjugated
200µl  $740.00

WWOX Antibody (aa369-396, APC) LS-C224668
Rabbit Polyclonal (IgG) to Mouse WWOX
Mouse
ELISA, WB
APC Conjugated
200µl  $740.00

WWOX Antibody (aa369-396, AP) LS-C224667
Rabbit Polyclonal (IgG) to Mouse WWOX
Mouse
ELISA, WB
AP Conjugated
200µl  $740.00

WWOX Antibody (aa369-396, Azide-free, HRP) LS-C224671
Rabbit Polyclonal (IgG) to Mouse WWOX
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

WWOX Antibody (aa369-396, PE) LS-C224672
Rabbit Polyclonal (IgG) to Mouse WWOX
Mouse
ELISA, WB
PE Conjugated
200µl  $740.00

WWOX Antibody LS-C771848
Rabbit Polyclonal (IgG) to Human WWOX
Human
ELISA, WB
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00

WWOX Antibody LS-C137023
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl  $275.00
Western blot Image

WWOX Antibody (aa1-50) LS-C119598
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysates from HepG2 cells, using WWOX Antibody. The lane on the right is blocked with the synthesized peptide.

WWOX Antibody LS-C83452
Rabbit Polyclonal (IgG) to Human WWOX
Mouse, Human
WB
Unconjugated
100µg  $395.00
Showing 1-25 of 41 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).