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WWC1 / KIBRA
WW and C2 domain containing 1
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
| Gene Name: | WW and C2 domain containing 1 |
| Synonyms: | WWC1, HBeAg-binding protein 3, HBEBP3, KIBRA, HBEBP36, KIAA0869, Kidney and brain protein, Protein KIBRA, Protein WWC1, WW domain-containing protein 1, WW and C2 domain containing 1 |
| Target Sequences: | NP_056053.1 Q8IX03 |
Publications (1)
1
Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway. Toloczko A, Guo F, Yuen HF, Wen Q, Wood SA, Ong YS, Chan PY, Shaik AA, Gunaratne J, Dunne MJ, Hong W, Chan SW. Cancer research. 2017 77:4921-4933. (WB; Human)
[Full Text Article]
[PubMed:28720576]
Related Antibodies: LS-C175353.
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WWC1 / KIBRA
(39)
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(23)
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(8)
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(38)
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WWC1 / KIBRA Mouse anti-Human Monoclonal (OTI1H8) Antibody
Human
WB
Unconjugated
100 µl/$434
WWC1 / KIBRA Mouse anti-Human Monoclonal (Carrier-free) (OTI1H8) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
WWC1 / KIBRA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
WWC1 / KIBRA Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
WWC1 / KIBRA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa286-313) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa286-313) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa286-313) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa286-313) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa286-313) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa286-313) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) Antibody
Mouse
WB
Unconjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$355; 200 µl/$417; 500 µl/$635; 1 ml/$792; 2 ml/$1,030; 5 ml/$1,803
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$366; 200 µl/$432; 500 µl/$683; 1 ml/$842; 2 ml/$1,088; 5 ml/$1,941
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$543; 200 µl/$732; 500 µl/$1,268; 1 ml/$1,585; 2 ml/$2,219; 5 ml/$4,159
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
WWC1 / KIBRA Rabbit anti-Mouse Polyclonal (aa847-1094) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773
WWC1 / KIBRA Mouse anti-Human Monoclonal (OTI1B1) Antibody
Human
WB
Unconjugated
100 µl/$434
WWC1 / KIBRA Mouse anti-Human Monoclonal (Carrier-free) (OTI1B1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
WWC1 / KIBRA Rabbit anti-Human Polyclonal (pSer947) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa793-842) Antibody
Human
WB
Unconjugated
100 µl/$424
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa793-842) (Biotin) Antibody
Mouse, Guinea pig, Horse, Orangutan, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
WWC1 / KIBRA Rabbit anti-Human Polyclonal (aa286-313) Antibody
Human
WB
Unconjugated
400 µl/$393
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