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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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WRNIP1 / WHIP

Werner helicase interacting protein 1

Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.

Gene Name: Werner helicase interacting protein 1
Synonyms: WRNIP1, Putative helicase RUVBL, WHIP, RP11-420G6.2, ATPase WRNIP1, BA420G6.2
Target Sequences: NM_020135 NP_064520.2 Q96S55

Viewing 1-19 of 19 items
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human WRNIP1 / WHIP
Mouse, Bovine, Rat, Hamster, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human WRNIP1 / WHIP
Mouse, Bovine, Rat, Hamster, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human WRNIP1 / WHIP
Mouse, Bovine, Rat, Hamster, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100µl   1mg/ml   $385.00
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human WRNIP1 / WHIP
Mouse, Bovine, Rat, Hamster, Bat, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100µl   1mg/ml   $385.00
WRNIP1 / WHIP Antibody - Anti-WRNIP1 / WHIP antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Mouse, Rat, Human, Monkey
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $485.00
WRNIP1 / WHIP Antibody - Detection of Human WRNIP1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-WRNIP1 used at a dilution of 1:250.
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Mouse, Human
IF, IHC
Unconjugated
100µl   $415.00
WRNIP1 / WHIP Antibody - Detection of Human WRNIP1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-WRNIP1 used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
IHC, IP, WB
Unconjugated
100µl   1mg/ml   $405.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
ELISA, WB
PE Conjugated
200µl   $740.00
WRNIP1 / WHIP Antibody - Goat Anti-WHIP / WRNIP1 Antibody (4µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.
Select
Goat Polyclonal to Human WRNIP1 / WHIP
Mouse, Dog, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
WRNIP1 / WHIP Antibody - Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE WRNIP1 / WHIP antibody diluted at 1:1000
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
WB
Unconjugated
100µl   0.69mg/ml   $355.00
WRNIP1 / WHIP Antibody - Western blot analysis of extracts of HeLa cells.
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00
WRNIP1 / WHIP Antibody - WRNIP1 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The WRNIP1 antibody detected the WRNIP1 protein (arrow).
Select
Rabbit Polyclonal to Human WRNIP1 / WHIP
Human
WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human WRNIP1 / WHIP
Human
Unconjugated
100µg   $435.00

Viewing 1-19 of 19 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).