WNT4

wingless-type MMTV integration site family, member 4

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

WNT4 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus + His, C-terminus (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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Human WNT4 Protein (Recombinant GST) (Full Length) - LS-G33961

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

65.5 kDa

Price:

2 µg/$439

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Human WNT4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85468

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

20 µg/$150

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WNT4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101959

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

100 µg/$494

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Human WNT4 Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G144817

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

64.6 kDa

Price:

50 µg/$419

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Human WNT4 Protein (Recombinant His-SUMO) (aa23-351) - LS-G21325

Source:

Yeast

Tag:

His-SUMO

Molecular Weight:

52.65 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human WNT4 Protein (Recombinant His-T7) (aa26-351) - LS-G26140

Source:

E. coli

Tag:

His-T7

Molecular Weight:

40.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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