WNK3 / PRKWNK3

WNK lysine deficient protein kinase 3

Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca2+ influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner.Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.

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Products

Antibodies (27)

Type

Primary (27)

Target

WNK3 / PRKWNK3 (27)

Reactivity

Human (27)

Mouse (8)

Rat (2)

Bat (3)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Pig (3)

Rabbit (3)

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Application

IHC (18)

IHC-P (5)

WB (10)

ELISA (17)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (27)

Product Group

IHCPlus (1)

Isotype

IgG (26)

Clonality

polyclonal pc (27)

Format

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (11)

Epitope

C-Terminus (6)

N-Terminus (6)

aa431-480 (4)

aa1-50 (1)

Publications

No (27)

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WNK3 / PRKWNK3 Antibody (aa431-480) LS-B12631

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (aa431-480) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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WNK3 / PRKWNK3 Antibody (aa431-480, HRP) LS-C451265

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (aa431-480) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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WNK3 / PRKWNK3 Antibody (aa431-480, Biotin) LS-C451263

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (aa431-480) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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WNK3 / PRKWNK3 Antibody (aa431-480, FITC) LS-C451264

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (aa431-480) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

WNK3 / PRKWNK3 Antibody LS-C809659

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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WNK3 / PRKWNK3 Antibody (C-Terminus) LS-C329111

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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WNK3 / PRKWNK3 Antibody (C-Terminus, Biotin) LS-C246403

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (C-Terminus, FITC) LS-C246404

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (C-Terminus, PE) LS-C246405

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (C-Terminus, APC) LS-C246401

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (C-Terminus, Azide-free, HRP) LS-C247977

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

Select

WNK3 / PRKWNK3 Antibody (N-Terminus) LS-C330737

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

Select

WNK3 / PRKWNK3 Antibody (N-Terminus, Biotin) LS-C246398

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (N-Terminus, FITC) LS-C246399

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (N-Terminus, APC) LS-C246397

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (N-Terminus, PE) LS-C246400

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

Select

WNK3 / PRKWNK3 Antibody (N-Terminus, Azide-free, HRP) LS-C247976

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (N-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

WNK3 / PRKWNK3 Antibody LS-C682338

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

WNK3 / PRKWNK3 Antibody (Biotin) LS-C681710

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

WNK3 / PRKWNK3 Antibody LS-C335585

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Rat Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

WNK3 / PRKWNK3 Antibody LS-C779120

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

WNK3 / PRKWNK3 Antibody (aa1-50) LS-C288656

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

WNK3 / PRKWNK3 Antibody LS-C750475

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

WNK3 / PRKWNK3 Antibody LS-C833494

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

WNK3 / PRKWNK3 Antibody LS-C817613

Antibody:

WNK3 / PRKWNK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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