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WLS / GPR177

wntless Wnt ligand secretion mediator

Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.

Gene Name:	wntless Wnt ligand secretion mediator
Synonyms:	WLS, C1orf139, G protein-coupled receptor 177, Protein wntless homolog, MRP, Wntless homolog (Drosophila), EVI, GPR177
Target Sequences:	NM_024911 NP_079187.3 Q5T9L3

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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