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WFDC12 is a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Gene Name: | WAP four-disulfide core domain 12 |
Synonyms: | WFDC12, DJ211D12.4, Single WAP motif protein 2, Protease inhibitor WAP2, SWAM2, WAP2, Whey acidic protein 2, C20orf122 |
Target Sequences: | NM_080869 NP_543145.1 Q8WWY7 |
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