WDYHV1

WDYHV motif containing 1

Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

WDYHV1 (5)

Publications

No (5)

Tag

GST, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Low Endotoxin Level

Low endotoxin level (2)

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Human WDYHV1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68663

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.5 kDa

Price:

20 µg/$1,107

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Human WDYHV1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82725

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.5 kDa

Price:

20 µg/$150

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WDYHV1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101522

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.5 kDa

Price:

100 µg/$494

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Human WDYHV1 Protein (Recombinant GST, N-terminus) (Met1-Cys205) - LS-G40066

Source:

E. coli

Tag:

GST, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49.8kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human WDYHV1 Protein (Recombinant GST, N-terminus) (Met1-Cys205) - LS-G139683

Source:

E. coli

Tag:

GST, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49.8 kDa

Price:

10 µg/$376; 50 µg/$526

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