Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
WDR9 / BRWD1 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.
Gene Name: | bromodomain and WD repeat domain containing 1 |
Synonyms: | BRWD1, C21orf107, N143, Transcriptional unit N143, WD repeat-containing protein 9, WD repeat domain 9, WDR9, WD repeat protein WDR9-form2 |
Target Sequences: | NM_018963 NP_061836.2 Q9NSI6 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.