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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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WDR5

WD repeat domain 5

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Gene Name: WD repeat domain 5
Synonyms: WDR5, BIG3, BIG-3, SWD3, WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WD repeat domain 5, WD-repeat protein 5
Target Sequences: AJ011376 CAB66159.1 P61964

Filtered By: None
Target
WDR5 (36)
Reactivity
Human (34)
Mouse (19)
Rat (13)
Bat (8)
Bovine (9)
Chicken (8)
Chimpanzee (6)
Dog (9)
Gibbon (6)
Guinea pig (9)
Hamster (8)
Horse (9)
Monkey (8)
Orangutan (3)
Pig (8)
Xenopus (6)
Zebrafish (6)
Application
IHC (8)
IHC-P (5)
WB (34)
ELISA (15)
ICC (2)
IF (6)
IP (1)
Peptide-ELISA (1)
PLA (1)
Host
rabbit (34)
mouse (1)
goat (1)
Isotype
IgG (21)
IgG2b (1)
Clonality
monoclonal mc (1)
polyclonal pc (35)
Clone
7B11 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (21)
Epitope
aa12-40 (8)
aa2-334 (4)
aa265-314 (4)
aa41-90 (4)
aa321-354 (2)
aa50-100 (2)
N-Terminus (1)
aa1-120 (1)
aa1-334 (1)
aa1-50 (1)
Publications
No (36)
Showing 1-25 of 36 results

WDR5 Antibody (N-Terminus) IHC-plus™ LS-B8824
Rabbit Polyclonal (IgG) to Human WDR5
Human
ICC IF IHC IHC-P WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-WDR5 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunocytochemistry of WDR5 in 293 cells with WDR5 antibody at 5 ug/ml.
Anti-WDR5 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunocytochemistry of WDR5 in 293 cells with WDR5 antibody at 5 ug/ml.

WDR5 Antibody (aa50-100) IHC-plus™ LS-B14433
Rabbit Polyclonal (IgG) to Human WDR5
Xenopus, Zebrafish, Rat, Mouse, Human
IF IHC IHC-P PLA WB
Unconjugated
100µl 0.2mg/ml  $485.00
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Mouse and Rat WDR5 by Western Blot. Samples: Whole cell lysate (50 ug) from NIH3T3, TCMK-1, 4T1, CT26.WT, and rat C6 cells. Antibodies: Affinity purified rabbit anti-WDR5 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Mouse and Rat WDR5 by Western Blot. Samples: Whole cell lysate (50 ug) from NIH3T3, TCMK-1, 4T1, CT26.WT, and rat C6 cells. Antibodies: Affinity purified rabbit anti-WDR5 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

WDR5 Antibody (aa50-100) IHC-plus™ LS-B14463
Rabbit Polyclonal (IgG) to Human WDR5
Xenopus, Zebrafish, Rat, Mouse, Human
IF IHC IHC-P
Unconjugated
50µl  $425.00
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

WDR5 Antibody LS-C482342
Rabbit Polyclonal to Human WDR5
Mouse, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $255.00; 100µl 1mg/ml  $295.00; 200µl 1mg/ml  $375.00
Immunohistochemical analysis of WDR5 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of WDR5 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Immunohistochemical analysis of WDR5 staining in human kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of WDR5 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.

WDR5 Antibody (aa41-90) LS-C117008
Rabbit Polyclonal to Human WDR5
Xenopus, Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
50µg  $365.00
WDR5 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
WDR5 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

WDR5 Antibody (aa1-334) LS-C376995
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA IHC IHC-P WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human breast using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human thyroid using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human breast using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human thyroid using antibody at 1:100 dilution.

WDR5 Antibody LS-C331830
Rabbit Polyclonal (IgG) to Human WDR5
Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human kidney cancer tissue.
Immunofluorescence analysis of U2OS cells.
Immunohistochemistry of paraffin-embedded human kidney cancer tissue.
Immunofluorescence analysis of U2OS cells.

WDR5 Antibody LS-C661607
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

WDR5 Antibody LS-C341407
Rabbit Polyclonal to Human WDR5
Mouse, Rat, Human
IHC WB
Unconjugated
100µl 1mg/ml  $385.00

WDR5 Antibody LS-C748625
Rabbit Polyclonal (IgG) to Human WDR5
Mouse, Human
IF WB
Unconjugated
50µl  $235.00
Immunofluorescence analysis of U2OS cells using WDR5 antibody.
Western blot analysis of extracts of various cell lines, using WDR5 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Immunofluorescence analysis of U2OS cells using WDR5 antibody.
Western blot analysis of extracts of various cell lines, using WDR5 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.

WDR5 Antibody (clone 7B11) LS-C169224
Mouse Monoclonal [clone 7B11] (IgG2b) to Human WDR5
Human
ELISA WB
Unconjugated
100µl  $345.00
Western blot using WDR5 mouse monoclonal antibody against HeLa (1) cell lysate.
Western blot using WDR5 mouse monoclonal antibody against HeLa (1) cell lysate.

WDR5 Antibody (aa12-40) LS-C326339
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
Unconjugated
200µl  $530.00

WDR5 Antibody (aa12-40, Biotin) LS-C224639
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

WDR5 Antibody (aa12-40, FITC) LS-C224640
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
FITC Conjugated
200µl  $680.00

WDR5 Antibody (aa12-40, APC) LS-C224638
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
APC Conjugated
200µl  $680.00

WDR5 Antibody (aa12-40, PE) LS-C224642
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
PE Conjugated
200µl  $680.00

WDR5 Antibody (aa12-40, AP) LS-C224637
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
AP Conjugated
200µl  $680.00

WDR5 Antibody (aa12-40, Azide-free, HRP) LS-C224641
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

WDR5 Antibody (aa2-334) LS-C370538
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
Unconjugated
50µg  $285.00; 100µg  $385.00

WDR5 Antibody (aa2-334, HRP) LS-C370539
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00

WDR5 Antibody (aa2-334, Biotin) LS-C370544
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

WDR5 Antibody (aa2-334, FITC) LS-C370540
Rabbit Polyclonal (IgG) to Human WDR5
Human
ELISA WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00

WDR5 Antibody LS-C347722
Rabbit Polyclonal (IgG) to Human WDR5
Mouse
ELISA WB
Unconjugated
50µl  $345.00

WDR5 Antibody (aa321-354) LS-C356323
Rabbit Polyclonal to Human WDR5
Mouse
Peptide-ELISA WB
Unconjugated
400µl  $305.00
Western blot of lysate from mouse NIH/3T3 cell line, using WDR5 antibody diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.
Western blot of lysate from mouse NIH/3T3 cell line, using WDR5 antibody diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.

WDR5 Antibody (aa265-314) LS-C145257
Rabbit Polyclonal to Mouse WDR5
Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Human, Monkey
WB
Unconjugated
50µg  $365.00
WDR5 antibody Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
WDR5 antibody Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 36 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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