WDR48

WD repeat domain 48

Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 by enhancing the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12 and USP46, respectively. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. In case of infection by Herpesvirus saimiri, may play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. Induces lysosomal vesicle formation via interaction with Herpesvirus saimiri tyrosine kinase-interacting protein (TIP). Subsequently, TIP recruits tyrosine-protein kinase LCK, resulting in down-regulation of T-cell antigen receptor TCR. May play a role in generation of enlarged endosomal vesicles via interaction with TIP. In case of infection by papillomavirus HPV11, promotes the maintenance of the viral genome via its interaction with HPV11 helicase E1.

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Products

Antibodies (11)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (11)

Recombinant (2)

Target

WDR48 (15)

Reactivity

Human (11)

Mouse (4)

Rat (4)

Application

IHC (10)

IHC-P (2)

WB (11)

Flo (7)

ELISA (6)

Host

rabbit (11)

Product Group

IHCPlus (1)

Isotype

IgG (9)

Clonality

polyclonal pc (11)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (6)

Epitope

aa603-630 (7)

Publications

No (15)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ WDR48 Antibody (aa603-630) LS-B11223

(4.0) Rating

Antibody:

WDR48 Rabbit anti-Human Polyclonal (aa603-630) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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WDR48 Antibody (aa603-630) LS-C326337

Antibody:

WDR48 Rabbit anti-Human Polyclonal (aa603-630) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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WDR48 Antibody (aa603-630, Biotin) LS-C273519

Antibody:

WDR48 Rabbit anti-Human Polyclonal (aa603-630) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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WDR48 Antibody (aa603-630, FITC) LS-C273520

Antibody:

WDR48 Rabbit anti-Human Polyclonal (aa603-630) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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WDR48 Antibody (aa603-630, APC) LS-C273518

Antibody:

WDR48 Rabbit anti-Human Polyclonal (aa603-630) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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WDR48 Antibody (aa603-630, Azide-free, HRP) LS-C273521

Antibody:

WDR48 Rabbit anti-Human Polyclonal (aa603-630) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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WDR48 Antibody (aa603-630, PE) LS-C273522

Antibody:

WDR48 Rabbit anti-Human Polyclonal (aa603-630) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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WDR48 Antibody LS-C409073

Antibody:

WDR48 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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WDR48 Antibody LS-C482713

Antibody:

WDR48 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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WDR48 Antibody LS-C771810

Antibody:

WDR48 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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WDR48 Antibody LS-C796601

Antibody:

WDR48 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$414

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Human WDR48 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G73490

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76 kDa

Price:

20 µg/$1,107

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Human WDR48 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G95382

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76 kDa

Price:

20 µg/$150

Select

Human WDR48 Protein (Recombinant GST) (Full Length) - LS-G34753

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

83 kDa

Price:

10 µg/$479; 25 µg/$670

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WDR48 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110946

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76 kDa

Price:

100 µg/$494

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