WAC

WW Domain Containing Adaptor With Coiled-coil

Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

WAC (4)

Publications

No (4)

Tag

6His-SUMO, N-terminus (1)

GST (1)

Myc-DDK (Flag) (2)

Species

Bacteriophage T4 (1)

Human (2)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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Bacteriophage T4 WAC Protein (Recombinant 6His-SUMO, N-terminus) (aa2-487) - LS-G57401

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human WAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90505

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

20 µg/$150

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Human WAC Protein (Recombinant GST) (Full Length) - LS-G33726

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

91.9 kDa

Price:

2 µg/$439

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WAC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112553

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

100 µg/$494

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