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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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VWF / Von Willebrand Factor
von Willebrand factor
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
| Gene Name: | von Willebrand factor |
| Synonyms: | VWF, Coagulation factor VIII VWF, F8VWF, VWD, Von Willebrand factor, factor VIII-related antigen, Factor VIII-R, Factor VIII-R Ag, VIII R AG |
| Target Sequences: | NM_000552 NP_000543.2 P04275 |
Publications (3)
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