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VTCN1 / B7-H4
V-set domain containing T cell activation inhibitor 1
Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
| Gene Name: | V-set domain containing T cell activation inhibitor 1 |
| Synonyms: | VTCN1, B7 superfamily member 1, B7 Superfamily, member 1, B7h.5, B7S1, B7H4, PRO1291, VCTN1, RP11-229A19.4, B7 family member, H4, B7-H4, B7X, Protein B7S1 |
| Target Sequences: | NM_024626 NP_078902.2 Q7Z7D3 |
☰ Filters
Products
Proteins
(22)
Type
Over-Expression Lysate
(2)
Recombinant
(20)
Target
VTCN1 / B7-H4
(22)
Publications
No
(22)
Tag
Fc
(2)
Fc, C-terminus
(4)
Fc-AVI, C-terminus
(1)
His
(3)
His,C-terminus
(3)
His-GST
(1)
Human IgG1 Fc
(1)
mFc, C-terminus
(1)
Mouse IgG2 Fc
(2)
Myc-DDK (Flag)
(2)
Rabbit IgG Fc, N-terminus
(1)
Species
Human
(15)
Monkey-Rhesus
(2)
Mouse
(4)
Source
293T Cells
(1)
CHO Cells
(3)
E. coli
(4)
HEK 293 Cells
(6)
Human
(1)
Human Cells
(2)
Mammalian Cells
(5)
Purification
Purified
(5)
Low Endotoxin Level
Low endotoxin level
(17)
Biologically Active
Biologically active
(2)
CHO Cells
Mouse IgG2 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$480
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.5 kDa
10 µg/$317; 50 µg/$524
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.4 kDa
10 µg/$266; 50 µg/$335
HEK 293 Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
52.2 kDa
100 µg/$721
HEK 293 Cells
Rabbit IgG Fc, N-terminus
Less than 5.0 EU/mg protein (determined by LAL method).
~85 kDa (SDS-PAGE)
100 µg/$480
Human
Fc-AVI, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
54.1 kDa
20 µg/$416; 100 µg/$910
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
293T Cells
Myc-DDK (Flag)
30.7 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
30.7 kDa
100 µg/$494
CHO Cells
Human IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$480
CHO Cells
Mouse IgG2 Fc
Biologically active
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$463
E. coli
155 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
17.16 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.8 kDa
100 µg/$721; 1 mg/$4,701
HEK 293 Cells
His,C-terminus
Less than 0.01 EU/µg protein (determined by LAL method).
~50 kDa (SDS-PAGE)
50 µg/$442
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.7 kDa
10 µg/$277; 50 µg/$389
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.5 kDa
10 µg/$297; 50 µg/$460
HEK 293 Cells
None
Less than 0.01 EU/µg protein (determined by LAL method).
~50 kDa (SDS-PAGE)
50 µg/$449
Mammalian Cells
mFc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51.9 kDa
10 µg/$281; 50 µg/$389
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.7kD
10 µg/$277; 50 µg/$395; 500 µg/$1,262; 1 mg/$1,627
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
52.3 kDa
100 µg/$926; 1 mg/$4,701
E. coli
His
14.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His-GST
42.3 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
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