VRK1

vaccinia related kinase 1

Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.

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Products

Antibodies (33)

Proteins (10)

ELISA Kits (1)

Type

Over-Expression Lysate (2)

Primary (33)

Recombinant (8)

Sandwich (1)

Target

VRK1 (44)

Reactivity

Human (34)

Mouse (12)

Rat (5)

Application

IHC (4)

IHC-P (1)

WB (32)

ELISA (11)

IF (2)

IP (4)

Peptide-ELISA (1)

RNAi (1)

Host

rabbit (26)

mouse (7)

Isotype

IgG (14)

IgG1 (5)

IgG2a,k (1)

Clonality

monoclonal mc (6)

polyclonal pc (27)

Clone

1015CT2.1.1 (1)

4F9 (1)

OTI2C9 (2)

OTI2E10 (2)

Format

96-Well Strip Plate (1)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (2)

Carrier-free (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (21)

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Epitope

aa46-292 (8)

aa366-396 (7)

aa1-230 (4)

aa1-396 (1)

aa1-50 (1)

aa292-329 (1)

aa346-396 (1)

Publications

No (44)

Sample Type

Plasma (1)

Serum (1)

Tag

10His, N-terminus + Myc, C-terminus (1)

6His, N-terminus + Myc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (7)

Mouse (2)

Source

293T Cells (1)

Baculovirus (1)

E. coli (3)

HEK 293 Cells (1)

Insect Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (2)

Select

VRK1 Antibody LS-C409296

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539

Select

VRK1 Antibody (clone 4F9) LS-C198432

Antibody:

VRK1 Mouse anti-Human Monoclonal (4F9) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, RNAi, WB

Format:

Unconjugated

Price:

100 µg/$423

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VRK1 Antibody LS-C676707

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

VRK1 Antibody LS-C831877

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

VRK1 Antibody LS-C489858

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

Select

VRK1 Antibody LS-C772436

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

VRK1 Antibody (aa366-396) LS-C330727

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa366-396) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

VRK1 Antibody (aa366-396, Biotin) LS-C284197

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa366-396) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

VRK1 Antibody (aa366-396, FITC) LS-C284199

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa366-396) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

VRK1 Antibody (aa366-396, APC) LS-C284196

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa366-396) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

VRK1 Antibody (aa366-396, Azide-free, HRP) LS-C284198

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa366-396) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

VRK1 Antibody (aa366-396, PE) LS-C284200

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa366-396) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

VRK1 Antibody LS-C780092

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

VRK1 Antibody (aa1-396) LS-C132837

Antibody:

VRK1 Mouse anti-Human Polyclonal (aa1-396) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

VRK1 Antibody (aa346-396) LS-C762786

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa346-396) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

VRK1 Antibody LS-C808314

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

VRK1 Antibody (clone 1015CT2.1.1) LS-C204029

Antibody:

VRK1 Mouse anti-Human Monoclonal (1015CT2.1.1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$393

Select

VRK1 Antibody (aa1-230, clone OTI2E10) LS-C339720

Antibody:

VRK1 Mouse anti-Human Monoclonal (aa1-230) (OTI2E10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

VRK1 Antibody (aa1-230, clone OTI2E10, Carrier-free) LS-C790711

Antibody:

VRK1 Mouse anti-Human Monoclonal (aa1-230) (Carrier-free) (OTI2E10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

VRK1 Antibody (aa1-230, clone OTI2C9) LS-C339654

Antibody:

VRK1 Mouse anti-Human Monoclonal (aa1-230) (OTI2C9) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

VRK1 Antibody (aa1-230, clone OTI2C9, Carrier-free) LS-C790666

Antibody:

VRK1 Mouse anti-Human Monoclonal (aa1-230) (Carrier-free) (OTI2C9) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

VRK1 Antibody (aa46-292) LS-C296933

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa46-292) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561

Select

VRK1 Antibody LS-C490578

Antibody:

VRK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

Select

VRK1 Antibody (aa292-329) LS-C408119

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa292-329) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

VRK1 Antibody (aa366-396) LS-C100604

Antibody:

VRK1 Rabbit anti-Human Polyclonal (aa366-396) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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