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May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.
Gene Name: | vacuolar protein sorting 54 homolog (S. cerevisiae) |
Synonyms: | VPS54, HVps54L, SLP-8p, Tumor antigen SLP-8p, VPS54L, WR, Tumor antigen HOM-HCC-8, HCC8 |
Target Sequences: | NM_016516 NP_057600.2 Q9P1Q0 |
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