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VPS52 / SACM2L

vacuolar protein sorting 52 homolog (S. cerevisiae)

May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.

Gene Name:	vacuolar protein sorting 52 homolog (S. cerevisiae)
Family/Subfamily:	Transporter
Synonyms:	VPS52, ARE1, DJ1033B10.5, SACM2L, RP5-1033B10, SAC2
Target Sequences:	NM_022553 NP_072047.4 Q8N1B4

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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