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May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.
Gene Name: | vacuolar protein sorting 52 homolog (S. cerevisiae) |
Family/Subfamily: | Transporter |
Synonyms: | VPS52, ARE1, DJ1033B10.5, SACM2L, RP5-1033B10, SAC2 |
Target Sequences: | NM_022553 NP_072047.4 Q8N1B4 |
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