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VPS39

vacuolar protein sorting 39 homolog (S. cerevisiae)

May play a role in clustering and fusion of late endosomes and lysosomes. Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription. Does not affect TGF-beta-induced SMAD2 or SMAD3 phosphorylation, nor SMAD2/SMAD4 complex formation.

Gene Name: vacuolar protein sorting 39 homolog (S. cerevisiae)
Synonyms: VPS39, HVam6p, KIAA0770, TRAP1-like protein, Vam6/Vps39-like protein, VAM6, TLP
Target Sequences: Q96JC1 Q96JC1

☰ Filters
Antibodies (10)
Proteins (4)
Over-Expression Lysate (2)
Primary (10)
Recombinant (2)
VPS39 (14)
Human (10)
Mouse (3)
Rat (1)
IHC (3)
IHC-P (2)
WB (6)
ELISA (6)
IF (3)
Peptide-ELISA (1)
rabbit (10)
Product Group
IHCPlus (1)
IgG (9)
polyclonal pc (10)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (7)
Internal (1)
aa630-868 (1)
No (14)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
VPS39 Antibody - Anti-VPS39 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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VPS39 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
VPS39 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue at dilution of 1:100
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VPS39 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
VPS39 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
VPS39 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
VPS39 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
VPS39 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
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VPS39 Rabbit anti-Human Polyclonal (aa630-868) Antibody
Human
ELISA
Unconjugated
100 µg/$351
VPS39 Protein - Purified recombinant protein VPS39 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
100.6 kDa
20 µg/$1,107
VPS39 Antibody - Western blot analysis of extracts of various cell lines, using VPS39 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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VPS39 Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
VPS39 Antibody - Western blot analysis of extracts of mouse brain tissue using VPS39 antibody. The lane on the left was treated with blocking peptide.
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VPS39 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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VPS39 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
VPS39 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
100.6 kDa
20 µg/$150
VPS39 Protein - 12.5% SDS-PAGE of human VPS39 stained with Coomassie Blue
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Wheat Germ Extract
GST
127.2 kDa
2 µg/$439
VPS39 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
100.6 kDa
100 µg/$494
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).