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VPS18
vacuolar protein sorting 18 homolog (S. cerevisiae)
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
| Gene Name: | vacuolar protein sorting 18 homolog (S. cerevisiae) |
| Synonyms: | VPS18, HVPS18, KIAA1475, PEP3 |
| Target Sequences: | AA082935 Q9P253 Q9P253 |
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