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VNN2

vanin 2

VNN2 is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Name: vanin 2
Synonyms: VNN2, FOAP-4, GPI-80, Pantetheinase, Protein FOAP-4, Vanin-2, Vanin 2, Vannin 2
Target Sequences: AJ132100 CAA10569.1 O95498

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
VNN2 (6)
No (6)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
HEK 293 Cells (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
VNN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.9 kDa
100 µg/$710
VNN2 Protein - 12.5% SDS-PAGE of human VNN2 stained with Coomassie Blue
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Wheat Germ Extract
GST
79.3 kDa
10 µg/$479; 25 µg/$670
VNN2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
VNN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
52.9 kDa
20 µg/$215
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.2 kDa
10 µg/$288; 50 µg/$436
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.23kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).