VNN1

Vanin 1

Vanin1 (pantetheinase) is an amidohydrolase that catalyzes the hydrolysis of D-pantetheine, permitting the recycling of pantothenate (vitamin B5) and the generation of an antioxidant metabolite, cysteamine. Vanin-1 is a glycosylphosphatidylinositol (GPI)-anchored molecule expressed by perivascular thymic stromal cells. Antibody against vanin-1 blocked thymus colonization by hematopoietic progenitor cells in both short- and long-term assays and interfered with lymphostromal cell adhesion. It is suggested that vanin-1 regulates late adhesion steps of thymus homing under physiologic, noninflammatory conditions. In addition the pantetheinase activity of the vanin-1 molecule is thought to be a major regulator of intestinal inflammation, acting through cysteamine release. Vanin1 (-/-) mice displayed a drastically reduced incidence of colorectal cancer.

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Products

ELISA Kits (12)

Type

Custom (4)

Development Kit (1)

Sandwich (7)

Target

VNN1 (12)

Reactivity

Human (6)

Mouse (2)

Rat (1)

Dog (1)

Pig (1)

Product Group

DevKit DuoPlus (1)

Format

96-Well Strip Plate (11)

Antibody Pair and Standard (1)

Publications

No (12)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (8)

Serum (8)

Tissue Homogenates (6)

Urine (3)

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Human VNN1 (Sandwich ELISA) ELISA Kit - LS-F12958

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human VNN1 (Sandwich ELISA) ELISA Kit - LS-F35951

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human VNN1 (Sandwich ELISA) ELISA Kit - LS-F6879

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$834

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DevKit DuoPlus Human VNN1 ELISA Development Kit - LS-F72026

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates, Urine

Price:

500 Wells/$1,276; 1000 Wells/$1,903

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Mouse VNN1 (Sandwich ELISA) ELISA Kit - LS-F39015

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

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Human VNN1 (Sandwich ELISA) ELISA Kit - LS-F52372

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Pig VNN1 (Custom ELISA) ELISA Kit - LS-F17289

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine VNN1 (Custom ELISA) ELISA Kit - LS-F17290

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse VNN1 (Custom ELISA) ELISA Kit - LS-F17291

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Dog VNN1 (Custom ELISA) ELISA Kit - LS-F17292

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Human VNN1 (Sandwich ELISA) ELISA Kit - LS-F38149

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat VNN1 (Sandwich ELISA) ELISA Kit - LS-F6858

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$893

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