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VKORC1

Vitamin K Epoxide Reductase Complex, Subunit 1

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.

Gene Name: Vitamin K Epoxide Reductase Complex, Subunit 1
Synonyms: VKORC1, EDTP308, MST134, MST576, IMAGE3455200, VKCFD2, VKOR
Target Sequences: NM_024006 NP_076869.1 Q9BQB6

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Products
Antibodies (16)
Primary (16)
VKORC1 (16)
Human (16)
Mouse (1)
Bat (3)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
Monkey (3)
Orangutan (3)
Rabbit (3)
IHC (9)
IHC-P (1)
WB (11)
ELISA (11)
ICC (1)
IF (2)
rabbit (16)
IgG (12)
polyclonal pc (16)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (5)
aa15-41 (6)
aa27-76 (4)
No (16)
VKORC1 Antibody - Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 ug/ml.
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VKORC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
VKORC1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VKORC1 Rabbit anti-Human Polyclonal (aa27-76) Antibody
Human
IHC, WB
Unconjugated
100 µl/$424
VKORC1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VKORC1 Rabbit anti-Human Polyclonal (aa27-76) (HRP) Antibody
Rabbit, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan
WB
HRP Conjugated
100 µl/$469
VKORC1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VKORC1 Rabbit anti-Human Polyclonal (aa27-76) (Biotin) Antibody
Rabbit, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan
WB
Biotin Conjugated
100 µl/$469
VKORC1 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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VKORC1 Rabbit anti-Human Polyclonal (aa27-76) (FITC) Antibody
Rabbit, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan
WB
FITC Conjugated
100 µl/$469
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VKORC1 Rabbit anti-Human Polyclonal (aa15-41) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
VKORC1 Antibody - Immunofluorescence staining of VKORC1 in MCF7 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human VKORC1 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm.
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VKORC1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
VKORC1 Antibody - Immunohistochemistry Dilution at 1:200 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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VKORC1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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VKORC1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
VKORC1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
VKORC1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-16 of 16 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).