VKORC1

Vitamin K Epoxide Reductase Complex, Subunit 1

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.

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Products

Antibodies (16)

ELISA Kits (6)

Proteins (4)

Type

Competitive EIA (1)

Custom (1)

Over-Expression Lysate (2)

Primary (16)

Recombinant (2)

Sandwich (4)

Target

VKORC1 (26)

Reactivity

Human (19)

Mouse (2)

Rat (1)

Bat (3)

Bovine (4)

Chimpanzee (3)

Gibbon (3)

Monkey (3)

Orangutan (3)

Rabbit (3)

Application

IHC (9)

IHC-P (1)

WB (11)

ELISA (11)

ICC (1)

IF (2)

Host

rabbit (16)

Isotype

IgG (12)

Clonality

polyclonal pc (16)

Format

96-Well Strip Plate (6)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (5)

Epitope

aa15-41 (6)

aa27-76 (4)

Publications

No (26)

Sample Type

Cell Lysates (1)

Plasma (4)

Serum (4)

Tissue Homogenates (2)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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VKORC1 Antibody LS-C153685

Antibody:

VKORC1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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VKORC1 Antibody (aa27-76) LS-C169733

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa27-76) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$424

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VKORC1 Antibody (aa27-76, HRP) LS-C470806

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa27-76) (HRP) Antibody

Reactivity:

Rabbit, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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VKORC1 Antibody (aa27-76, Biotin) LS-C470804

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa27-76) (Biotin) Antibody

Reactivity:

Rabbit, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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VKORC1 Antibody (aa27-76, FITC) LS-C470805

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa27-76) (FITC) Antibody

Reactivity:

Rabbit, Bovine, Bat, Gibbon, Human, Monkey, Chimpanzee, Orangutan

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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Mouse VKORC1 (Sandwich ELISA) ELISA Kit - LS-F14672

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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VKORC1 Antibody (aa15-41) LS-C326281

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa15-41) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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VKORC1 Antibody (aa15-41, Biotin) LS-C273338

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

VKORC1 Antibody (aa15-41, FITC) LS-C273339

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

VKORC1 Antibody (aa15-41, APC) LS-C273337

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

VKORC1 Antibody (aa15-41, Azide-free, HRP) LS-C273340

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

VKORC1 Antibody (aa15-41, PE) LS-C273341

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (aa15-41) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

VKORC1 Antibody LS-C817590

Antibody:

VKORC1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

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VKORC1 Antibody LS-C681686

Antibody:

VKORC1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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VKORC1 Antibody (HRP) LS-C681687

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

VKORC1 Antibody (Biotin) LS-C681685

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

VKORC1 Antibody (FITC) LS-C681688

Antibody:

VKORC1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human VKORC1 (Sandwich ELISA) ELISA Kit - LS-F33862

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat VKORC1 (Custom ELISA) ELISA Kit - LS-F14673

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human VKORC1 (Sandwich ELISA) ELISA Kit - LS-F25522

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

Human VKORC1 Protein (Recombinant GST) (Full Length) - LS-G35119

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

44.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human VKORC1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69817

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.7 kDa

Price:

20 µg/$1,107

Select

Human VKORC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85608

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.1 kDa

Price:

20 µg/$150

Select

VKORC1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101853

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.1 kDa

Price:

100 µg/$494

Select

Bovine VKORC1 (Competitive EIA) ELISA Kit - LS-F12956

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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