Vitamin D Receptor / VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

The vitamin D receptor, a NR1 Thyroid Hormone-Like Receptor, is activated by calcitriol, the active hormonal form of vitamin D. The activated receptor binds DNA at a specific vitamin D-responsive element and promotes transcription of vitamin D target genes such as osteocalcin, the most abundant noncollagenous protein in bone. The vitamin D receptor affects growth, bone formation, and female reproduction. For example, this receptor modulates the growth and differentiation of keratinocytes and mediates the beneficial effects of vitamin D on psoriatic skin. It also inhibits hormone secretion by and proliferation of parathyroid cells. The vitamin D receptor functions either as a homodimer or as a heterodimer of vitamin D and retinoid acid X receptor subunits. Inactivation of the receptor leads to hypocalcemia and Rickets-alopecia syndrome. Recently, the vitamin D receptor has been shown to function as a receptor for the secondary bile acid lithocholic acid (LCA), which is hepatotoxic and a potential enteric carcinogen. Activation of VDR by LCA or vitamin D induced expression in vivo of CYP3A, a cytochrome P450 enzyme that detoxifies LCA in the liver and intestine. An alternatively spliced vitamin D receptor that has an altered ligand-binding domain has been isolated from rats.

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Products

ELISA Kits (26)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Competitive EIA (2)

Custom (5)

Development Kit (1)

Sandwich (15)

Sandwich CLIA (1)

Target

Vitamin D Receptor / VDR (26)

Reactivity

Human (8)

Mouse (5)

Rat (4)

Chicken (2)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (3)

96-Well Strip Plate (21)

Antibody Pair and Standard (1)

Publications

No (25)

Yes (1)

Sample Type

Adherent Cell Cultures (2)

Cell Culture Supernatants (1)

Cell Lysates (4)

Plasma (9)

Serum (9)

Tissue Homogenates (8)

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Human Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F5306

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Human Phospho-Vitamin D Receptor / VDR (Ser208) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1444

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Human Vitamin D Receptor / VDR (Cell-Based ELISA) ELISA Kit - LS-F2387

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Chicken Vitamin D Receptor / VDR (Custom ELISA) ELISA Kit - LS-F14613

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Rat Vitamin D Receptor / VDR (Custom ELISA) ELISA Kit - LS-F14614

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse Vitamin D Receptor / VDR (Custom ELISA) ELISA Kit - LS-F14615

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Pig Vitamin D Receptor / VDR (Custom ELISA) ELISA Kit - LS-F14616

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine Vitamin D Receptor / VDR (Custom ELISA) ELISA Kit - LS-F14617

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human Vitamin D Receptor / VDR (CLIA) ELISA Kit - LS-F30197

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse Vitamin D Receptor / VDR (Competitive EIA) ELISA Kit - LS-F28654

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Human Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F22604

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F27316

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

2.5 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Human Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F33483

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F33484

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F33485

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Monkey Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F49075

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Guinea pig Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F49074

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Chicken Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F49073

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Porcine Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F49076

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Rabbit Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F49077

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Sheep Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F49078

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$760

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Rat Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F54064

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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DevKit DuoPlus Mouse Vitamin D Receptor / VDR ELISA Development Kit - LS-F71689

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,207; 1000 Wells/$1,787

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Rat Vitamin D Receptor / VDR (Sandwich ELISA) ELISA Kit - LS-F8750

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$818

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Human Vitamin D Receptor / VDR (Competitive EIA) ELISA Kit - LS-F12930

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.624 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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