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VDAC2

voltage-dependent anion channel 2

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.

Gene Name:	voltage-dependent anion channel 2
Family/Subfamily:	Ion Channel , VDAC porin
Synonyms:	VDAC2, B-36 vdac, HVDAC2, Porin-2, VDAC-2, Vdac6
Target Sequences:	NM_003375 NP_003366.2 P45880

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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