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VDAC1 / PORIN

voltage-dependent anion channel 1

Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.

Gene Name: voltage-dependent anion channel 1
Family/Subfamily: Ion Channel , VDAC porin
Synonyms: VDAC1, HVDAC1, Plasmalemmal porin, Porin 31HM, PORIN, PORIN-31-HL, Vdac5, VDAC, Mitochondrial porin, Porin 31HL, VDAC-1
Target Sequences: NM_003374 NP_003365.1 P21796

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
VDAC1 / PORIN (7)
No (7)
GST (1)
GST, N-terminus (3)
His-GST (1)
Myc-DDK (Flag) (2)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (4)
Purified (1)
VDAC1 / PORIN Protein - Recombinant Voltage Dependent Anion Channel Protein 1 By SDS-PAGE
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E. coli
His-GST
90.6 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
VDAC1 / PORIN Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
VDAC1 / PORIN Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
VDAC1 / PORIN Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
VDAC1 / PORIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
30.6 kDa
20 µg/$150
VDAC1 / PORIN Protein - 12.5% SDS-PAGE of human VDAC1 stained with Coomassie Blue
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Wheat Germ Extract
GST
57.2 kDa
10 µg/$479; 25 µg/$670
VDAC1 / PORIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
30.6 kDa
100 µg/$494
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).