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VCL / Vinculin

vinculin

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Gene Name: vinculin
Family/Subfamily: Cytoskeleton
Synonyms: VCL, CMD1W, CMH15, Metavinculin, Vinculin, MVCL
Target Sequences: NM_014000 NP_054706.1 P18206

☰ Filters
Products
Proteins (11)
Over-Expression Lysate (2)
Recombinant (9)
VCL / Vinculin (11)
No (11)
GST (2)
His (2)
His, N-Terminal (1)
His,C-terminus (1)
Myc-DDK (Flag) (3)
Human (8)
Mouse (2)
293T Cells (1)
E. coli (5)
HEK 293 Cells (3)
Human Cells (1)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (4)
VCL / Vinculin Protein
Select
E. coli
His, N-Terminal
24.7 kDa
10 µg/$281; 50 µg/$442; 200 µg/$882; 1 mg/$1,989; 5 mg/$3,081; 2 mg/$2,176
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
117.0 kDa
10 µg/$317; 50 µg/$524
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
118 kDa
50 µg/$721
VCL / Vinculin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
116.5 kDa
100 µg/$494
VCL / Vinculin Protein - 12.5% SDS-PAGE of human VCL stained with Coomassie Blue
Select
Wheat Germ Extract
GST
143 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
GST
53.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
VCL / Vinculin Protein - Purified recombinant protein VCL was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
116.5 kDa
20 µg/$1,107
VCL / Vinculin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
116.5 kDa
20 µg/$150
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
118.2 kDa
50 µg/$710
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
117kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
VCL / Vinculin Protein - Recombinant Vinculin By SDS-PAGE
Select
E. coli
His
14.6 kDa
10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107
Viewing 1-11 of 11 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).