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VAMP7 / SYBL1 / T1 VAMP

vesicle-associated membrane protein 7

Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation.

Gene Name: vesicle-associated membrane protein 7
Synonyms: VAMP7, Synaptobrevin-like protein 1, Tetanus-insensitive VAMP, SYBL1, Synaptobrevin-like 1, VAMP-7, TI-VAMP, TIVAMP
Target Sequences: NM_005638 NP_005629.1 P51809

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).