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VAMP1 / VAMP-1
vesicle-associated membrane protein 1 (synaptobrevin 1)
Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
| Gene Name: | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| Family/Subfamily: | Synaptobrevin |
| Synonyms: | VAMP1, SYB1, Synaptobrevin 1, VAMP-1, Synaptobrevin-1 |
| Target Sequences: | NM_016830 NP_058439.1 P23763 |
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