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SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for SUMO2 and SUMO3 which it cleaves more efficiently. Also able to process full-length SUMO proteins to their mature forms. May have non-catalytic functions in Cajal bodies organization and cell proliferation.
Gene Name: | ubiquitin specific peptidase like 1 |
Synonyms: | USPL1, BA121O19.1, C13orf22, D13S106, D13S106E, Highly charged protein, RP11-121O19.1 |
Target Sequences: | NM_005800 NP_005791.3 Q5W0Q7 |
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